|
GZL SERIES VACUUM FREEZING DRYER
The freeze drier made by our company is
designed and manufactured strictly according to GMP Specifications, and has
the following merits:
●
All the parts contacting the
products are made of ALSL 316L
stainless steel, the surface roughness reaches R a≤0.5u m.
●
The inner circle of the chest has a
smooth transition without dead corner, no objects accumulated.
●
Consider for user, the structure is
easy to clean.
●
Option for steam sterilization or
chemical sterilization.
Except for the above, our company can also
provide automatic running CIP(on-site cleaning) and SIP(steam sterilization)
functions to ensure the high quality of cleaning and the sterilization of the
equipment.
SIP:
¬ Use
overheats pure steam (121℃).
¬ Equipped
with cooling water jacket, after sterilizing, it can fast reduce the
temperature of the chest (if less than 20㎡, the equipment is standard
configuration.)
¬ Optional
pneumatic door lock, it locks automatically.
¬ Use
import sterilization filter to ensure the absolutely sterilized air coming
into equipment.
¬ The
chest and various kinds of container and tube are all wrapped with import
insulating layer to efficiently avoid from heat transmission.
¬ Can
carry out constant humidity control to the refrigeration humidity.
¬ Equipped
with water circulation pump capable to eliminate residual water in
sterilization layer.
CIP:
¬ The
high –pressure clean water thoroughly wash inner surface of the chest and
condenser.
¬ Equipped
with large flow rate CIP pump.
¬ Fixed
with CIP tubing that automatically drains the residual water.
¬ Use
rotary fixed nozzle with 360-degree spray.
¬ The
hydraulic system uses isolated retractable corrugated tube.
The
freeze drier made by our company has a proper layout and enough space to
benefit the maintenance and operation of the equipment.
¬ Square
or round shape chest(use may choose one of them)
¬ Horizontal
of vertical condenser
¬ Integral
design can fully use space.
¬ Separate
design can make each component independent, easy to operate and maintain.
¬ Working
temperature scope of condenser: -8℃( when it is dry)~+121℃(when
in steam sterilizing).
¬ Pressure
scope of the chest:1Pa
¬ Use
industrial pressure container standard: GB150-1998 series.
¬ Conform
to national vacuum equipment standard: GB/T3163-3164
¬ GMP
and FDA relevant regulations.
¬ Standard
of international Electrotechnical Commission(IEC)
¬ China
Electric Equipment Standard(GB)
¬ The
chest, lamellar and condenser is make of AISI316L stainless steel.
¬ TIG
welding avoids gap that can not be cleaned and possible leakage.
¬  The
welding point the tube is photographed with X-ray, with inspection record and
certification of qualification.
¬ The
roughness of inner surface reaches R a≤0.5u, mirror polished.
¬ Leakage
rate of the system≤ 5*10(-2) mbar 1/s to ensure normal and reliable
running.
¬ There
is no dead corner in the chest, the connection of tube is simple and
reasonable, easy to clean.
The freeze drier uses the best
refrigeration system to freeze the product and condensate the steam produced
during freeze-drying procedure. Freeze-drying technology requires the
refrigeration system to keep a low temperature status for a long period of
time, therefore, the requirements to the refrigeration system are very high. But
the freeze drier of our company can easily help you to reach your goal.
¬ Use
world famous brand, e.g. Frascold, Danfoss, Copeland, Castel, Edwards, and
etc.
¬ The
system uses double stage half sealed piston compressor to reach first class
temperature reducing speed rate and the lowest temperature in China.
¬ The
system power equipped is much greater than needed to efficiently ensure the
refrigeration performance.
¬ Digital
and module design has a high protection to ensure the system to run normally
and stably.
¬ The
powerful refrigeration system, liquid spray cooling system and other
protection installations keep to the best working temperature and high system
reliability.
¬ The
sensitive transducing system can provide alarm and protection in time against
abnormal running situation.
¬ Uses
refrigeration conforming to the world environment protection requirement,
such as HCFCR22 and HFCRA for choice.
¬ Special
synthetic lubricating oil can eliminate various kinds of problem due to high
temperature of normal mineral oil.
 The
vacuum system of the freeze drier providers a necessary pressure environment
to freeze drying procedure. Cooperating with condenser, it can reach the
vacuum leaver required by the freeze-drying procedure. To make the system run
stably under high vacuum situation. The key point is the performance of the
vacuum pump, and the valve, seal and instrument that cooperate with the pump.
The vacuum system of our freeze drier has
the following characteristic:
¬  Standard
configuration, uses Edwards double stage oil sealing revolving plate pump.
¬ Option:
Edwards pump
¬ Equipped
with two vacuum probes, for measuring the vacuum level of freeze drying chest
and pump resectively.
¬ Option:
condenser type vacuum meter.
¬ There
are two methods for drying chest vacuum level control:
1.
Drying chest vacuum level controls
the opening and closing of the air inlet valve, introduce the sterilized air
from sterilized room.
2.
Drying chest vacuum level controls
the opening degree of the big butterfly valve to reach the purpose of
controlling the vacuum level.
The drying chest and water capture valve,
circulating pump, spotlight and etc. of the freeze drier, like other
components of the freeze drier, use the first class components from other countries
or from domestic factories.
The above systems of our freeze drier have
the following characteristics:
¬ A
couple-clamping butterfly valve is equipped between the drying chest and
water capture to keep a no leakage seal in both directions.
¬ Use
labial margin seal design to compensate the change of temperature and
pressure during operation.
¬ Eccentric
valve rod and eccentric butterfly valve eliminate the wear-out of upper and
lower ends of valve seat during frequent opening.
¬ May
choose electric of pneumatic driving device.
¬ Import
original electric driver can stepless adjust the opening wideness of
butterfly valve, control the vacuum level of the drying chest to avoid from
being polluted.
¬ Stainless
steel valve body and TEF elastic valve seat conform with GMP specification.
¬ The
drying chest and water capturer are equipped with viewing glass. The viewing
glass can be equipped with spotlight to obtain clear procedure monitoring.
¬ 
Shelf
refrigerating heating system uses Denmark Grundfos UPS circulation pump, Sweden
plate type heat exchanger, The size of the exchanger is small, this reduces
the heat conduction mediator and energy consumption, raises the refrigeration
efficiency.
The control system of the freeze drier
provides a reliable whole procedure control for the freeze drier. It has
advanced functions of display, control, recording, printing and alarming.
The control system of our freeze drier has
the following characteristics:
¬
 The
mains air switch, transformer and AC contactor fixed in electric cabinet are
Siemens products. The electric cabinet is secured on machine frame. All
machine pump motors are equipped with overheat protection, solenoid valve and
heating circuit are equipped with separate protection.
¬ The
display screen uses Mitsubishi touch screen, PLC programmable logic
controller, indicating light, sound-light alarming system, and etc.
¬ Temperature
measuring, pressure measuring, the components can work normally under high
temperature, ultra-low temperature and high vacuum level with high reliability.
¬ The
control system can display the running status of all components of the whole
system, and can store and process the operation information and various data.
It can provide procedure recording report of whole freeze-drying process. It can
alarm on failure or abnormal situation, provide checking for maintenance, the
operator can set and modify data and steps.
Our company operates it’s own internal
Quality Management system that provides the foundation for ISO 9001
accreditation. This system provides the basis for comprehensive documentation
of the manufacture of all its products, ensuring customers are provided with
full details of their equipment.
Standard documentation supplied with every
freeze dryer includes:
¬ electrical
diagram
¬ P&L
diagram
¬ Component
list
¬ Certificates
of conformance for
¬ Critical
components
¬ Operating
instructions
¬ Maintenance
instructions
¬ Copies
of pressure vessel certificates
Our company also able to provide IQ and OQ
documentation to assist customers with equipment validation. Calibration
documentation is also available. These services are not part of the standard
scope of supply.
Specification
|
Model
|
GZL0.5
|
GZL1
|
GZL2
|
GZL3
|
GZL6
|
GZL8
|
GZL10
|
GZL15
|
GZL20
|
GZL30
|
GZL40
|
GZL50
|
|
Lamel lay area(㎡)
|
0.5
|
1
|
2
|
3
|
6
|
8
|
10
|
15
|
20
|
30
|
40
|
50
|
|
Lamel lay size(mm)
|
405*
610
|
405*
610
|
610*
810
|
810*
915
|
915*
1215
|
915*
1215
|
1215*
1215
|
1215*
1615
|
1520*
1615
|
1520*
1615
|
1520*
1615
|
1520*
1615
|
|
Number
of lamel lay
|
2+1
|
4+1
|
4+1
|
4+1
|
5+1
|
7+1
|
7+1
|
8+1
|
10+1
|
10+1
|
16+2
|
20+2
|
|
Lamel lay spacing(mm)
|
90
|
100
|
100
|
100
|
100
|
100
|
100
|
100
|
100
|
100
|
100
|
100
|
|
Lamel lay smoothness(mm/m)
|
±0.1
|
±0.1
|
±0.1
|
±0.1
|
±0.2
|
±0.2
|
±0.2
|
±0.2
|
±0.2
|
±0.2
|
±0.2
|
±0.2
|
|
Lamel lay surface roughness(Ra)
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
0.8
|
|
Lamel lay lowest temperature(℃)
|
-50~-60
|
-50~-60
|
-50~-60--50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
-50~-60
|
|
Lamel lay temperature scope (℃)
|
-60/+121
|
|
Shape
of chest
|
Cylinder
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
Rectangular
|
|
Chest
inner surface polish
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
Mirror
|
|
Structure
and shape of water capturer
|
Horizontal
cylinder
|
Horizontal vertical
cylinder
|
Horizontal
cylinder
|
|
Lowest
temperature of water capturer(℃)
|
-80
|
-80
|
80
|
-80
|
80
|
-80
|
80
|
-80
|
80
|
-80
|
80
|
-80
|
|
Capturing
amount of water capturer(kg)
|
7.5
|
15
|
30
|
45
|
90
|
120
|
150
|
225
|
300
|
450
|
600
|
750
|
|
Refrigerator
power
|
1*5hp
|
1*5hp
|
1*10hp
|
1*10hp
|
2*10hp
|
2*15hp
|
2*15hp
|
2*25hp
|
2*30hp
|
3*30hp
|
4*30hp
|
4*30hp
|
|
Vacuum
suction rate(m3/h )
|
18
|
30
|
40
|
60
|
80
|
120
|
160
|
240
|
350
|
525
|
700
|
825
|
|
Control
system
|
Automatic + manual
|
|
Power
of whole machine(kw)
|
5
|
7.5
|
12
|
20
|
40
|
50
|
55
|
75
|
100
|
125
|
180
|
220
|
|
Cooling
water amount(T/H)
|
Cooling by air
|
2
|
4
|
4
|
8
|
12
|
12
|
20
|
24
|
36
|
48
|
48
|
|
Hydraulic
plug(option)
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
|
Hydraulic
plug(option) Hydraulic plug separation corrugated tube(option)
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
|
SIP(option)
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
|
CIP(option)
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
|
Freeze-drying
plate(option)
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
|
Diagram
recording instrument
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
√
|
|
Weight
of whole machine(kg)
|
2000
|
3000
|
3500
|
5000
|
6500
|
7500
|
9000
|
12500
|
13800
|
17800
|
22800
|
26000
|
|
External
size(L*W*H (m) )
|
1500*
1000*
2300
|
2280*
950*
2520
|
2752*
1302*
2650
|
3100*
1650*
2930
|
3630*
1950*
3600
|
3630*
1950*
3600
|
4100*
2300*
3600
|
6165*
2524*
3700
|
6165*
2524*
4050
|
6165*
2800*
4050
|
5500*
5000*
4530
|
5500*
5000*
5130
|
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